We offer complete solutions for 3D cell culture. Choose from our range of hydrogel precursor solutions and crosslink the hydrogels with light from one of our easy to use and portable crosslinkers.
Tens of thousands of academic and industrial laboratories apply cell culture to study the biology of cells that regulate health and disease, to identify and develop new drugs, and even find ways to grow replacement tissues for implantation. But there is a major problem with the way cells are cultured in most laboratories. Cells are grown on flat, unphysiologically stiff materials such as polystyrene and glass, causing them to display aberrant behaviors: flattened shape, abnormal polarisation, altered response to pharmaceutical reagents, and general loss of phenotype. Although scientists agree that traditional cell culture methods fail to recapitulate the native cellular microenvironment, there is a lack of easy-to-use and widely applicable systems that are capable of recreating such environments in the laboratory while providing consistent properties from batch-to-batch.
LunaGel™ is a photocrosslinkable hydrogel cell culture system that recreates the natural extracellular matrix (ECM) surrounding cells in the human body, allowing researchers to grow three-dimensional microscopic tissues, rather than just cells on plastic surfaces. The major components of LunaGel™ include native ECM proteins such as collagen type I, III, IV, and V, as well as connective tissue glycoproteins and proteoglycans. LunaGel™ retains the intrinsic cell-instructive bioactivity of natural ECMs, facilitating cell attachment, proliferation, differentiation, migration, and proteolytic degradation.