LunaGel™ - Hyaluronic acid (HA) is photocrosslinkable extracellular matrix based on high molecular weight HA, a linear polysaccharide consisting of alternating D-glucuronic acid and N-acetyl-D-glucosamine units found in connective tissues. LunaGel™ - HA has applications as a matrix for 3D cell culture, tissue engineering, 3D bioprinting, and drug delivery. 
 
Product Overview
The major components of LunaGel™ include the ECM proteins collagen type I, III, IV, and V, as well as connective tissue glycoproteins and proteoglycans. LunaGel™ retains the intrinsic cell-instructive bioactivity of natural ECMs facilitating cell attachment, proliferation, differentiation, migration, and proteolytic degradation. LunaGel™’s unique photocrosslinking technology allows unprecedented control over matrix porosity and stiffness, allowing researchers to replicate the physicochemical properties of a variety of healthy and diseased tissues in 3D cell culture applications.
 
LunaGel™ ECM has been successfully used in a wide range of applications including
cell attachment and proliferation
stem cell culture and differentiation
mechanotransduction assays
cancer spheroid assays
angiogenesis assays
3D bioprinting
tissue engineering
and more
 
How LunaGel™  Photocrosslinkable Extracellular Matrix​ Works
LunaGel™ is supplied as a sterile solution with freeze-dried photoinitiator. Available as Low Stiffness (0 - 6.5 kPa) and High Stiffness kit (0 - 25 kPa). Reconstitute the photoinitiator in PBS, mix with LunaGel™ ECM and cells, and photocrosslink the solution using the  Luna Crosslinker™ to form 3D cell culture models. By controlling the duration of light exposure you can produce hydrogels with a specified stiffness. Add your favourite culture media and you're culturing in 3D!